Dengue
What is dengue?
Dengue
(pronounced den' gee) is a disease caused by any one
of four closely related viruses (DEN-1, DEN-2, DEN-3,
or DEN-4). The viruses are transmitted to humans by
the bite of an infected mosquito. In the Western Hemisphere,
the Aedes aegypti mosquito is the most important transmitter
or vector of dengue viruses.
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What is dengue haemorrhagic fever (DHF)?
DHF
is a more severe form of dengue. It can be fatal if
unrecognised and not properly treated. DHF is caused
by infection with the same viruses that cause dengue.
With good medical management, mortality due to DHF can
be less than 1%. |
How are dengue and dengue hemorrhagic fever
(DHF) spread?
Dengue
is transmitted to people by the bite of an Aedes mosquito
that is infected with a dengue virus. The mosquito becomes
infected with dengue virus when it bites a person who
has dengue or DHF and after about a week can transmit
the virus while biting a healthy person. Dengue cannot
be spread directly from person to person. |
What are the symptoms of the disease?
The
principal symptoms of dengue are high fever, severe
headache, backache, joint pains, nausea and vomiting,
eye pain, and rash. Generally, younger children have
a milder illness than older children and adults.
Dengue hemorrhagic fever is characterized by a fever
that lasts from 2 to 7 days, with general signs and
symptoms that could occur with many other illnesses
(e.g., nausea, vomiting, abdominal pain, and headache).
This stage is followed by hemorrhagic manifestations,
tendency to bruise easily or other types of skin haemorrhages,
bleeding nose or gums, and possibly internal bleeding.
The smallest blood vessels (capillaries) become excessively
permeable ("leaky"), allowing the fluid component
to escape from the blood vessels. This may lead to failure
of the circulatory system and shock, followed by death,
if circulatory failure is not corrected. |
What is the treatment for dengue?
There
is no specific medication for treatment of a dengue
infection. Persons who think they have dengue should
use analgesics (pain relievers) with acetaminophen and
avoid those containing aspirin. They should also rest,
drink plenty of fluids, and consult a physician. |
Is
there an effective treatment for dengue hemorrhagic
fever (DHF)?
As
with dengue, there is no specific medication for DHF.
It can however be effectively treated by fluid replacement
therapy if an early clinical diagnosis is made. Hospitalisation
is frequently required in order to adequately manage
DHF. |
What
can be done to reduce the risk of acquiring dengue?
There
is no vaccine for preventing dengue. The best preventive
measure for residents living in areas infested with
Aedes aegypti is to eliminate the places where the mosquito
lays her eggs, primarily artificial containers that
hold water.
Items that collect rainwater or are used to store water
(for example, plastic containers, big drums, buckets,
or used automobile tires) should be covered or properly
discarded. Pet and animal watering containers and vases
with fresh flowers should be emptied and scoured at
least once a week. This will eliminate the mosquito
eggs and larvae and reduce the number of mosquitoes
present in these areas.
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- Tests
for Dengue.
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CBC - WBC Count, Platelet Count, Haematocrit.
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S. Protien, S. Albumin.
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Liver Function Tests.
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Urine - microscopic haematuria.
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Dengue IgG & IgM.
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The
tests for diagnosis of dengue infection are time dependent.
If the patient presents within the first 5 days after
onset of symptoms, which is the acute phase of the illness,
a blood sample should be drawn immediately, to be tested
for virus isolation. Virus can be isolated most easily
in samples drawn in the first days after onset of symptoms,
although it has been isolated as long as 12 days after
onset.
A convalescent-phase sample should also be drawn to
test for IgM antibody. This sample should be drawn between
6 and 21 days after symptom onset.
If the patient presents six or more days after symptom
onset, the blood sample should be drawn as soon as possible.
This sample should then be tested for serum IgM antibody.
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